Twynsta 80mg/5mg B/30Tab

Description: Twynsta is used to treat high blood pressure (hypertension). It contains a combination of amlodipine and telmisartan. Amlodipine is a calcium channel blocker. It relaxes (widens) blood vessels and improves blood flow. Telmisartan is an angiotensin II receptor antagonist. It keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.

Indications/Uses
Treatment of essential hypertension in adults: Add on therapy: TWYNSTA 40 mg/5 mg is indicated in adults whose blood pressure is not adequately controlled on amlodipine 5 mg alone.
TWYNSTA 40 mg/10 mg is indicated in adults whose blood pressure is not adequately controlled on amlodipine 10 mg alone.
TWYNSTA 80 mg/5 mg is indicated in adults whose blood pressure is not adequately controlled with TWYNSTA 40 mg/5 mg.
TWYNSTA 80 mg/10 mg is indicated in adults whose blood pressure is not adequately controlled on TWYNSTA 40 mg/10 mg or TWYNSTA 80 mg/5 mg.
Replacement therapy: Adult patients receiving telmisartan and amlodipine from separate tablets can instead receive tablets of TWYNSTA containing the same component doses.

Dosage/Direction for Use:
Posology: The recommended dose of this medicinal product is one tablet per day.
The maximum recommended dose is one tablet 80 mg telmisartan/10 mg amlodipine per day. This medicinal product is indicated for long term treatment.
Administration of amlodipine with grapefruit or grapefruit juice is not recommended as bioavailability may be increased in some patients resulting in increased blood pressure lowering effects (see Interactions).