Description:
Amoxicillin-clavulanate (beta-lactam antibacterial penicillin coformulated with a betalactamase inhibitor) is an antibiotic agent with a notably broad spectrum of activity
against the commonly occurring bacterial pathogens in general practice and hospital. The
beta-lactamase inhibitory action of clavulanate extends the spectrum of amoxycillin to
embrace a wider range of organisms, including many resistant to other beta-lactam
antibiotics.
Indication:
Amoxicillin-clavulanate should be used in accordance with local official antibioticprescribing guidelines and local susceptibility data.
Dosage:
Dosage depends on the age, weight and renal function of the patient and the severity of
the infection.
Dosages: are expressed throughout in terms of amoxicillin/clavulanate content except
when doses are stated in terms of an individual component.
To minimise potential gastrointestinal intolerance, administer at the start of a meal.
The absorption of amoxicillin-clavulanate is optimised when taken at the start of a meal.
Treatment should not be extended beyond 14 days without review.
Therapy can be started parenterally and continued with an oral preparation
